Commonly known as the “morning sickness”, the initial symptoms experienced during being pregnant are nausea and vomiting which are brought about by the hormonal changes taking place in the body. Up to 90% of women complain of the condition. Pregnant women develop nausea and vomiting on during the first trimester of being pregnant early.
The symptoms peak between six and eight weeks, receding around 12 weeks of being pregnant eventually. Morning sickness persists after 20 weeks of pregnancy rarely. If it can, the condition is known as “Hyperemesis Gravidarum”, a disorder that affects about 35% of the pregnant women, proving to be quite debilitating with profound physical and psychosocial consequences. Nausea and vomiting can be adequately managed in most of the ladies by drinking plenty of water and by preventing the foods that bring on the bouts of nausea and vomiting. If the symptoms preserve after these measures even, antiemetic drugs are recommended to the women that are pregnant. Is It Safe to Use Antiemetic in Pregnancy?
It is quite a common notion that taking antiemetics can change out to be dangerous during being pregnant. However, this myth must be busted as many of the antiemetic drugs have been proven to be safe for use in women that are pregnant. Unlike the popular idea, antiemetics are not associated with any increased risk of birth problems, low delivery weight in neonates, preterm delivery and still births, if they are taken during the first 13 weeks of pregnancy.
Since the symptoms top during the first trimester, of morning sickness is during that time the ideal time to begin the treatment. It has been proven that fast drug treatment with antiemetics yields greater results clinically. Usually, Hyperemesis Gravidarum can be handled in the outpatient section effectively. However, such cases often get neglected resulting in severe dehydration and weight loss. Despite the changes in lifestyle and conservative management, nearly 10% of the women that are pregnant continue to experience severe nausea and vomiting.
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Numerous antiemetic drugs have been proven to be safe and effective for use during pregnancy. However, these drugs are prescribed only after weighing their advantages against their potential hazards. Following antiemetic drugs are commonly prescribed for the treating nausea and vomiting in pregnant women. The first line antiemetic agent recommended for vomiting and nausea is metoclopramide, recommended at a dosage of 10 milligrams to be studied thrice daily.
The efficiency of metoclopramide has shown through rigorous clinical trials. The next medication of preference for vomiting and nausea, if metoclopramide fails to yield advantageous results, is Prochlorperazine which is one of the grouped family of phenothiazines. It really is commonly given at a dose of 5 milligrams three times a day. The relative part effects of Prochlorperazine to watch out for include extreme sedation and nervous system disorders. The next drug preferred for the management of excessive vomiting and nausea is Cyclizine, which is an antihistaminic drug, taken at a dose of 50 milligrams 3 x a day.
Cyclizine can also cause excessive sedation. Another secure and efficient antiemetic in pregnancy that should be used if the above mentioned drugs neglect to control the symptoms of nausea and vomiting is Promethazine. The drug is started at a dose of 25 milligrams to be studied prior to going to bed and the dosage is gradually stepped up till it reaches the maximal allowed medication dosage of 100 milligrams.